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Influence of rapid‐ and slow‐rate resorption collagen membrane in maxillary sinus augmentation
Author(s) -
Bresaola Marco Dapievi,
Matsumoto Mariza Akemi,
Zahoui Abbas,
Biguetti Claudia Cristina,
NaryFilho Hugo
Publication year - 2017
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1111/clr.12801
Subject(s) - resorption , maxillary sinus , immunolabeling , membrane , histopathology , immunohistochemistry , bone resorption , dentistry , chemistry , anatomy , pathology , medicine , biochemistry
Abstract Objective To evaluate the effects of low‐ and rapid‐resorption‐rate bioabsorbable collagen membranes in maxillary sinus augmentation procedure in rabbits considering Schneiderian membrane ( SM ) reaction and bone tissue formation. Materials and methods Eighteen male adult rabbits underwent bilateral maxillary sinus augmentation with particulate bovine hydroxyapatite to be divided into three groups, as follows: Group C – control, no membrane; Group RR – rapid resorbable collagen membrane; and Group SR – slow‐resorbable collagen membrane. The animals were euthanized after 30 and 120 days for specimen's removal to be prepared and analyzed under light microscopy, histomorphometry, and immunohistochemistry for Runx2 and VEGF labeling. Results Histopathology evaluation presented similar healing pattern among the groups with a satisfactory response of SM , both at day 30 and day 120. Bone histomorphometry did not reveal significant differences among the groups, as well as immunohistochemistry analysis, which presented intense immunolabeling for both proteins in all groups. Conclusions The presence of both membranes did not negatively interfere in bone formation and remodeling, and the focal mild inflammatory reaction caused by their degrading process did not impair the reconstructive procedure.