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Retracted: Bone neo‐formation and mineral degradation of 4Bone. ® Part II : histological and histomorphometric analysis in critical size defects in rabbits
Author(s) -
CalvoGuirado José Luis,
MatéSánchez Jose E.,
DelgadoRuiz Rafael A.,
Romanos Georgios E.,
De AzaMoya Piedad,
Velázquez Pablo
Publication year - 2015
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1111/clr.12465
Subject(s) - ceramic , porosity , biomedical engineering , implant , biocompatible material , materials science , bone mineral , chemistry , bone formation , dentistry , composite material , surgery , medicine , pathology , osteoporosis
Objective To carry out the histological and histomorphometric plus radiological analysis of biphasic ceramic. Materials and method In this study, porous HA /β TCP (4Bone ® ) ceramic material was tested for the bone repairing capacity and osteoinductive potential in a New Zealand rabbit model. The ratio of the ceramic′s components HA /β TCP was 60/40 (in wt%). Results The 4Bone ® showed significantly more bone formation in the pores and in the periphery of the graft than the control group. Histomorphometric analysis revealed that the ceramic material (66.43% ± 0.29) produced higher values of bone‐to‐implant contact ( BIC ) percentages (higher quality, closer contact); moreover, defect closure was significative higher in relation with control group (64.15% ± 3.52). Conclusions 4Bone ® is a biocompatible, partially resorbable and osteoconductive grafting material. Biphasic graft material of HA /β TCP with a porosity of 95% without loading favors new bone formation.