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Microradiography and microcomputed tomography comparative analysis in human bone cores harvested after maxillary sinus augmentation: a pilot study
Author(s) -
Soardi Carlo Maria,
Clozza Emanuele,
Turco Gianluca,
Biasotto Matteo,
Engebretson Steven P.,
Wang HomLay,
Zaffe Davide
Publication year - 2014
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1111/clr.12225
Subject(s) - maxillary sinus , medicine , soft tissue , nuclear medicine , x ray microtomography , sinus (botany) , computed tomography , tomography , implant , dentistry , radiology , surgery , biology , botany , genus
Objectives The aim of this study was to compare microradiography ( MR ) and microcomputed tomography (μ CT ) analysis of bone samples following maxillary sinus augmentation at different time periods and determine the relationships between measured area and volume fractions. Materials and methods Lateral window sinus grafts were performed on 10 patients using a mineralized human bone allograft ( MHBA ). At implant placement, 5–13 months after surgery, 10 bone core biopsies were harvested. Prior to histologic sectioning, bone samples were evaluated with μ CT . The morphometric parameters computed by MR and μ CT were compared using Pearson's correlation and Bland and Altman analysis and included hard tissue fraction ( HV / TV :%), soft tissue fraction ( SV / TV :%), vital bone fraction ( BV / TV :%) and residual graft fraction ( GV / TV :%). Results Strong positive correlation between MR and μ CT was found for HV / TV and SV / TV and BV / TV [ r = 0.84, 0.84 and 0.69, respectively] but weak for GV / TV [ r = 0.10]. Conclusion μ CT technology shows promising potential as an indicator of bone morphology changes; however, caution should be used in interpreting morphometric parameters, as the different methods reveal important biases.