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The influence of bone marrow aspirates and concentrates on the early volume stability of maxillary sinus grafts with deproteinized bovine bone mineral – first results of a RCT
Author(s) -
Kühl S.,
Payer M.,
Kirmeier R.,
Wildburger A.,
Wegscheider W.,
Jakse N.
Publication year - 2014
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1111/clr.12101
Subject(s) - maxillary sinus , medicine , sinus (botany) , dentistry , mann–whitney u test , sinus lift , bone marrow , surgery , nuclear medicine , pathology , botany , biology , genus
Objectives The aim of the study was to investigate whether bone marrow aspirates ( BMA ) and concentrates ( BMAC ) influence the grafts' stability when added to deproteinized bovine bone mineral ( DBBM ) within the first 6 months after maxillary sinus augmentation. Material and methods 26 CT data of 13 patients undergoing bilateral maxillary sinus augmentation in a split‐mouth design were evaluated using the Voxim ® software by comparing the graft volumes 2 weeks after the sinus lift procedure with CT data obtained 6 months later. DBBM with ( N = 6) or without tibial BMA ( N = 6) and DBBM with ( N = 7) and without adding iliac BMAC ® ( N = 7) were used as grafts. Absolute and percentage changes in the graft volumes were evaluated, and the nonparametric M ann– W hitney U ‐test and the nonparametric Wilcoxon test were performed to determine significant differences between the graft volumes within each single split‐mouth group and between the two groups. Results Overall, the volumes decreased between 15% and 21%. All single groups showed statistically significant decreases over 6 months of healing. The time‐dependent changes in volumes between the different groups were not statistically significant ( P = 0.818). Conclusions An evident decrease in graft volume over the first 6 months of healing has to be expected irrespectively of graft composite. Neither BMA nor BMAC seem to have an evident impact. Overaugmentation seems recommendable in two‐stage maxillary sinus surgery.