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Horizontal ridge augmentation using GBR with a native collagen membrane and 1:1 ratio of particulate xenograft and autologous bone: A 3‐year after final loading prospective clinical study
Author(s) -
Meloni Silvio Mario,
Jovanovic Sascha Alexander,
Urban Istvan,
Baldoni Edoardo,
Pisano Milena,
Tallarico Marco
Publication year - 2019
Publication title -
clinical implant dentistry and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 85
eISSN - 1708-8208
pISSN - 1523-0899
DOI - 10.1111/cid.12808
Subject(s) - medicine , implant , dentistry , bleeding on probing , maxilla , radiography , prospective cohort study , mandible (arthropod mouthpart) , surgery , botany , biology , genus , periodontal disease
Background Cawood‐Howell class IV atrophies, also known as “knife‐edge” ridges, represent a serious horizontal defect, making the placement of regular implants challenging. Aim To clinically and radiographically evaluate bone regeneration of severe horizontal bone defects with 3 years of follow‐up. Materials and Methods This study was designed as a single cohort, prospective clinical trial. Patients having horizontal bone width of 4 mm or less in the posterior mandible or maxilla were treated with resorbable collagen membranes and a 1:1 mixture of anorganic bovine bone (ABB) and autogenous bone. Implants were inserted and loaded 7 months later. Outcomes were implant and prosthetic survival rates, any biological and prosthetic complications, horizontal and volumetric bone dimensional changes measured on cone beam computer tomography (CBCT), peri‐implant marginal bone level (MBL) changes measured on periapical radiographs, plaque index (PI), and bleeding on probing (BOP). Results Eighteen patients received 55 implants. No patient dropped‐out. No implant and prosthetic failures and no complications were recorded. Super imposition of pre and 7‐month postoperative CBCT scans revealed an average horizontal bone gain of 5.03 ± 2.15 mm (95% CI: 4.13‐5.92 mm). After 3 years, mean MBL was 1.15 ± 0.28 mm (95% CI 0.84‐1.22 mm). The PI was 11.6%, and BOP was 5.2%. Conclusion Within the limitations of the present study, high implant survival rate and high average bone augmentation seem to validate the use of collagen resorbable membranes with a 1:1 mixture of particulate ABB and autogenous bone for the reconstruction of Cawood‐Howell class IV alveolar ridge atrophies.