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The applications of regenerative medicine in sinus lift procedures: A systematic review
Author(s) -
Correia Francisco,
Pozza Daniel Humberto,
Gouveia Sónia,
Felino António,
Faria e Almeida Ricardo
Publication year - 2018
Publication title -
clinical implant dentistry and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 85
eISSN - 1708-8208
pISSN - 1523-0899
DOI - 10.1111/cid.12561
Subject(s) - sinus lift , medicine , cochrane library , randomized controlled trial , medline , regenerative medicine , clinical trial , medical physics , systematic review , web of science , national library , dentistry , surgery , meta analysis , implant , pathology , library science , computer science , stem cell , biology , political science , law , genetics
Abstract Background Findings in regenerative medicine applied to the sinus lift procedures. Purpose Evaluate the effectiveness of regenerative medicine in sinus lift. Materials and Methods An extensive search for manuscripts were performed by using different combinations of keywords and MeSH terms (Pub‐med; Embase; Scopus; Web of Science Core Collection; Medline; Current Contents Connect; Derwent Innovations Index; Scielo Citation Index; Cochrane library). The full text selected articles are written in English, Portuguese, Spanish, Italian, German, or French, and published until 28 of November 2016. Inclusion criteria were: implant osteointegration, radiographic, histologic, and/or histomorphometric analysis, clinical studies in humans using of regenerative medicine. This systematic review was performed by selecting only randomized controlled clinical trials and controlled clinical trials. Results Eighteen published studies (11 CT and 7 RCT) were considered eligible for inclusion in the present systematic review. These studies demonstrated considerable variation of biomaterial and cell technics used, study design, sinus lift technic, outcomes, follow‐up, and results. Conclusion Only few studies have demonstrated potential of regenerative medicine in sinus lift; further randomized clinical trials are needed to achieve more accurate results.