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Comparison of allografts and xenografts used for alveolar ridge preservation. A clinical and histomorphometric RCT in humans
Author(s) -
Serrano Méndez Carlos Alberto,
Lang Niklaus Peter,
Caneva Martina,
Ramírez Lemus Gloria,
Mora Solano Gerardo,
Botticelli Daniele
Publication year - 2017
Publication title -
clinical implant dentistry and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 85
eISSN - 1708-8208
pISSN - 1523-0899
DOI - 10.1111/cid.12490
Subject(s) - medicine , alveolar ridge , dentistry , transplantation , ridge , dental alveolus , cortical bone , cancellous bone , implant , anatomy , surgery , biology , paleontology
Background Several types of bone grafts are used in ridge preservation procedures. Purpose To compare the healing of allografts and xenografts applied for alveolar ridge preservation. Materials and Methods Twenty volunteers in need of extraction of a single‐rooted tooth prior to implant installation were randomized into two groups. One group received a deproteinized cancellous bovine bone xenograft embedded in a 10% collagen matrix and the other a demineralized freeze‐dried cortical bone allograft. A collagen membrane was used to cover the grafts, flaps were sutured. At baseline and 6 months later, clinical measurements including vertical and horizontal bone dimensions were taken. Histomorphometric analysis was performed. Results Both groups showed shrinkage of bone dimensions. At mesial, center and distal sites, the vertical changes in dimension were −0.6, 0.5, and −0.1 mm for the allograft and −1.1, −0.4, and −0.9 mm for the xenograft. The horizontal changes in dimensions were −1.4 mm for the allograft and −2.6 mm for the xenograft. New bone and residual graft material were 25.5 ± 10.1% and 33.8 ± 9.4% at the allograft and 35.3 ± 16.8% and 22.2 ± 13.4% at the xenograft sites. None of the differences was statistically significant. Conclusion Both grafting materials are suitable for the preservation of the alveolar ridge.