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Biomechanical and Histomorphometrical Evaluation of TiZr Alloy Implants: An in vivo Study in the Rabbit
Author(s) -
Jimbo Ryo,
Naito Yoshihito,
Galli Silvia,
Berner Simon,
Dard Michel,
Wennerberg Ann
Publication year - 2015
Publication title -
clinical implant dentistry and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 85
eISSN - 1708-8208
pISSN - 1523-0899
DOI - 10.1111/cid.12305
Subject(s) - osseointegration , tibia , in vivo , femur , medicine , implant , dentistry , rabbit (cipher) , surgery , biology , microbiology and biotechnology , statistics , mathematics
Background Clinically, there is a demand for mechanically stronger alloyed implants; however, not much evidence exists with regard to these materials. Purpose To test the osseointegration property of TiZr 1317 implants in a rabbit model. Materials and Methods Hydrophilic titanium–zirconium alloy ( TiZr 1317) implants with sand‐blasted and acid‐etched surface (test) and hydrophilic cpTi implants with the same treatment (control) were placed pairwise in the hind limbs (two in each tibia and one in each femur) of 36 Swedish lop‐eared rabbits. After 2, 4, and 12 weeks ( n = 12/time point), the bone samples were subjected to removal torque ( RTQ , proximal tibia and femur) and histologic/histomorphometric (distal tibia) testings. Results The control presented significantly higher RTQ than the test at 2 weeks (55 vs 36 Ncm). No differences were observed for other time points. The test presented higher mean BIC than the control (19.25 vs 13.89 %) at 4 weeks; however, there were no statistical differences for the following time point tested in vivo.The new bone area was significantly higher for the test at 4 weeks in the marrow areas. Conclusion The TiZr 1317 implants presented comparable biologic outcomes to that of the cpTi implants through a 12‐week evaluation period.