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Lateral Bone Window Closing Technique with Poly‐ L ‐Lactic Acid ( PLLA ) Membrane in the Augmentation of the Maxillary Sinus without Grafting Material: Evaluation of Bone Healing in a Rabbit Model
Author(s) -
Kusumoto Yuki,
Tachikawa Noriko,
Munakata Motohiro,
Miyahara Takayuki,
Kasugai Shohei
Publication year - 2016
Publication title -
clinical implant dentistry and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 85
eISSN - 1708-8208
pISSN - 1523-0899
DOI - 10.1111/cid.12293
Subject(s) - maxillary sinus , membrane , sinus (botany) , biomedical engineering , grafting , bone grafting , materials science , sinus lift , dentistry , medicine , chemistry , composite material , biology , polymer , biochemistry , botany , genus
Background When augmenting the maxillary sinus without grafting material, the method used to cover the bony window is a subject of debate. Purpose The purpose of this study was to evaluate the poly‐ L ‐lactic acid ( PLLA ) membrane as closing material of the lateral window in a maxillary sinus augmentation without bone grafting. Materials and Methods Augmentation of the maxillary sinus without grafting material and installation of titanium screws that fix the Schneiderian membrane were performed in 18 Japanese male white rabbits. The bony window was covered with a collagen membrane or PLLA membrane or no membrane. The animals were sacrificed at 4 or 8 weeks. New bone volume was calculated radiologically using microcomputed tomography (micro‐ CT ). The samples were analyzed histologically after toluidine blue staining. Results No significant differences were observed in the new bone volume, as measured by micro‐ CT . However, histomorphometric analysis demonstrated the superiority of the PLLA membrane in new bone formation compared with the collagen membrane. Conclusion The PLLA membrane is a suitable material to be applied for tissue regeneration in this animal model.