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Life cycle of SARS‐CoV‐2: from sketch to visualization in atomistic resolution
Author(s) -
Bedřich Beneš,
Helwig Hauser
Publication year - 2021
Publication title -
computer graphics forum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 120
eISSN - 1467-8659
pISSN - 0167-7055
DOI - 10.1111/cgf.14200
Subject(s) - sketch , visualization , computer science , covid-19 , computer graphics (images) , artificial intelligence , algorithm , medicine , disease , pathology , infectious disease (medical specialty)
Description: The image shows the process of converting a scientific sketch into a 3D molecular visualization. We see a virion of SARSCoV-2 whose spike protein has just attached to an ACE-2 receptor of an epithelial cell. To illustrate this process, the scene was roughly sketched by an illustrator. The sketch was then converted into a 3D visualization by using an atomistic model of the virion created by statistical modeling. The scene was then rendered in real-time by an impostor-based molecular visualization algorithm. The virion model is accompanied by the procedurally generated cell membrane populated by lipids and protein molecules. The background, which shows epithelial cells and their cilia, was modeled and rendered in Blender and composed into the visualization to provide the viewers with a context.