Facial weakness and oligosyndactyly: ? independent variable features of familial type of the Möbius syndrome

A family consisting of two daughters, one with an isolated oligosyndactyly and the other with the Möbius Syndrome (VIth and VIIth nerve dysplasia) is presented. The majority of the individuals previously reported with an association of occulo‐facial diplegia and limb anomalies have been sporadic. However, on examination of the parents in the family we report, the mother was found to have bilateral facial weakness. Isolated limb anomalies may, therefore, be a variable expression of a broad spectrum type of the Möbius Syndrome, with an autosomal dominant mode of inheritance.