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The importance of precision medicine in modern molecular oncology
Author(s) -
Wang Yuanli,
Zheng Dawu
Publication year - 2021
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/cge.13998
Subject(s) - precision medicine , dna sequencing , computational biology , data science , proteomics , genetic diagnosis , genomics , genome , dna microarray , genomic medicine , bioinformatics , computer science , medicine , biology , dna , genetics , gene , gene expression
With the rapid development of modern medical technology, information data modeling has been gradually applied to clinical diagnosis and treatment. Precision medicine is an important approach that focuses on individual patients in terms of their own characteristics, genomic information, proteomics and even social environments. Genome‐wide high‐throughput technologies, including DNA‐seq, RNA‐seq, exosome‐seq…, contribute enormous amounts of molecular data to aid in diagnosis and analysis. Here, we review the developmental history of different next‐generation sequencing platforms, introduce their applications in different tumor diagnosis and therapy, and further discuss the remaining challenges in precision medicine.