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Hypertrophic pyloric stenosis in twins; genetic or environmental factors
Author(s) -
Gezer H.Ö.,
Oguzkurt P.,
Temiz A.,
Hicsonmez A.
Publication year - 2015
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/cge.12399
Subject(s) - hypertrophic pyloric stenosis , medicine , pyloric stenosis , cardiology
The etiology of infantile hypertrophic pyloric stenosis ( IHPS ) remains obscure. Over 120 years after the condition has become a clinical entity the debate whether the cause of IHPS is genetic, environmental or both, has not yet reached a final conclusion. Herein, we present a pair of monozygotic male twins with IHPS together with a review of the literature. We aimed to support genetic pre‐disposition in the epidemiology of IHPS , adding a twin data to the literature and to review the associated articles about the pathogenesis and inheritance patterns.