KCNT1 mutations in ADNFLE and MMPSI : a new driver in the etiology and pathophysiology of early‐onset epileptic syndromes

Missense mutations in the sodium‐gated potassium channel gene KCNT1 cause severe autosomal dominant nocturnal frontal lobe epilepsy Heron et al. (2012) Nature Genetics 44(11): 1188–1190. De novo gain‐of‐function KCNT1 channel mutations cause malignant migrating partial seizures of infancy Barcia et al. (2012) Nature Genetics 44(11): 1255–1259.