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Nationwide survey of maternal screening for mother‐to‐child infections in J apan
Author(s) -
Yamada Hideto,
Tairaku Shinya,
Morioka Ichiro,
Ebina Yasuhiko,
Sonoyama Ayako,
Tanimura Kenji,
Deguchi Masashi,
Nagamata Satoshi
Publication year - 2014
Publication title -
congenital anomalies
Language(s) - English
Resource type - Journals
eISSN - 1741-4520
pISSN - 0914-3505
DOI - 10.1111/cga.12044
Subject(s) - medicine , cytomegalovirus , treponema , pregnancy , hepatitis b virus , rubella virus , rubella , obstetrics , hepatitis b , pediatrics , virus , syphilis , virology , immunology , human immunodeficiency virus (hiv) , vaccination , viral disease , biology , herpesviridae , measles , genetics
Mother‐to‐child infections cause congenital infection with disease and sequelae. To evaluate a state of maternal blood screening for mother‐to‐child infections in J apan, we for the first time conducted a nationwide survey on obstetric facilities where regular maternity checkups were carried out. A questionnaire assessment involved an annual number of deliveries, scale of facilities and a state of maternal blood screening for eight pathogens. A high rate (73.7%) of reply to the questionnaire was achieved from 1990 facilities, covering 75.1% of annual number of delivery in 2011. The performance rates of blood screening were more than 99% for rubella virus, T reponema pallidum , human immunodeficiency virus ( HIV ), human T cell leukemia virus type 1 ( HTLV ‐1), hepatitis B virus, and hepatitis C virus, while the rate was found to be only 4.5% for cytomegalovirus ( CMV ), and 48.5% for T oxoplasma gondii with large differences in regions. Most of the facilities performed blood tests for rubella virus, T reponema pallidum , HIV , hepatitis B virus and hepatitis C virus once in early pregnancy, while approximately 28% of the facilities performed blood tests for HTLV ‐1 once during the 2nd or 3rd trimester. Most of the facilities used HA tests for T oxoplasma gondii , whereas there was a wide variation in antibody measurement methods for CMV . Generally, the obstetric facilities in J apan have performed maternal blood screening properly according to the current recommendations. The results of this survey involve important information and are helpful for clinical practitioners.