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Long‐term survival rates of patients undergoing vitrectomy for diabetic retinopathy in an Australian population: a population‐based audit
Author(s) -
Liu Ebony,
Estevez Jose,
Kaidonis Georgia,
Hassall Mark,
Phillips Russell,
Raymond Grant,
Saha Niladri,
Wong George H.C.,
Gilhotra Jagjit,
Burdon Kathryn,
Landers John,
Henderson Tim,
Newland Henry,
Lake Stewart,
Craig Jamie E.
Publication year - 2019
Publication title -
clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 1442-6404
DOI - 10.1111/ceo.13466
Subject(s) - medicine , diabetic retinopathy , population , dialysis , proportional hazards model , retrospective cohort study , kidney disease , mortality rate , survival rate , diabetes mellitus , environmental health , endocrinology
Abstract Importance Five‐year survival rates in patients undergoing vitrectomy for diabetic retinopathy (DR) vary from 68% to 95%. No study has been conducted in an Australian population. Background We aimed to determine the survival rates of patients undergoing diabetic vitrectomy in an Australian population. Design Retrospective audit, tertiary centre hospitals and private practices. Participants All individuals in South Australia and the Northern Territory who underwent their first vitrectomy for diabetic complications between January 1, 2007 and December 31, 2011. Methods An audit of all eligible participants has been completed previously. Survival status as of July 6, 2018 and cause of death were obtained using SA/NT DataLink. Kaplan‐Meier survival curves and multivariate cox‐regressions were used to analyse survival rates and identify risk factors for mortality. Main outcome measures Five‐, seven‐ and nine‐year survival rates. Results The 5‐, 7‐ and 9‐year survival rates were 84.4%, 77.9% and 74.7%, respectively. The most common cause of death was cardiovascular disease. Associated with increased mortality independent of age were Indigenous ethnicity (HR = 2.04, 95% confidence interval [CI]: 1.17‐3.57, P = 0.012), chronic renal failure (HR = 1.76, 95% CI: 1.07‐2.89, P = 0.026) and renal failure requiring dialysis (HR = 2.32, 95% CI: 1.25‐4.32, P = 0.008). Conclusions and relevance Long‐term survival rates after diabetic vitrectomy in Australia are similar to rates reported in other populations. Indigenous ethnicity and chronic renal failure were the most significant factors associated with long‐term mortality. This information can guide allocation of future resources to improve the prognosis of these high risk groups.