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Evaluation of stability and capsular bag opacification of a new foldable adjustable intraocular lens
Author(s) -
MacLean Kyle D,
Werner Liliana,
Kramer Gregory D,
Farukhi M Aabid,
Gardiner Gareth L,
Kahook Malik Y,
Mamalis Nick
Publication year - 2015
Publication title -
clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 1442-6404
DOI - 10.1111/ceo.12526
Subject(s) - medicine , posterior capsule opacification , ophthalmology , lens (geology) , phacoemulsification , enucleation , intraocular lens , surgery , visual acuity , optics , physics
Background Incorrect lens power remains one of the most common reasons for intraocular lens explantation/exchange. We evaluated stability and effect on capsular bag opacification of a new foldable modular lens system, with a base component and an optic component in rabbit eyes. Methods Bilateral phacoemulsification was performed on six rabbits; one eye received the test lens ( H armoni M odular L ens, ClarVista M edical), whereas the other received a single‐piece hydrophobic acrylic control lens ( SA60AT , A lcon). Slit‐lamp examinations were performed at postoperative weeks 1, 2, 3, 4 and 6. All rabbits were sacrificed at week 6. After enucleation, the eyes were examined grossly from the M iyake– A pple view. Following, all globes were sectioned and processed for histopathological examination. Results The modular lens was stable in all six rabbits. Uveal biocompatibility was similar to or better in the test eyes when compared with control eyes up to 6 weeks postoperatively. Overall, capsular bag opacification was found to be significantly lower in the test eyes when compared with control eyes. At the 6‐week gross examination, central posterior capsule opacification was scored as 0.58 ± 0.73 in the test group, and as 3.00 ± 1.26 in the control group (paired two samples for means t ‐test; two‐tail P = 0.005). Conclusions The H armoni M odular system remains stable within the capsular bag after implantation. Due to the design of the base component featuring long loops, along with peripheral anterior and posterior square edges, the lens appeared to prevent overall capsular bag opacification in the rabbit model.