Premium
Pregnancy in multiple sclerosis: A reflection on the importance of individualizing management
Author(s) -
Pinto Maria João,
Seabra Mafalda,
Sá Maria José,
Guimarães Joana
Publication year - 2021
Publication title -
clinical and experimental neuroimmunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 15
ISSN - 1759-1961
DOI - 10.1111/cen3.12622
Subject(s) - multiple sclerosis , pregnancy , medicine , mirroring , disease , gestation , obstetrics , pediatrics , psychology , immunology , genetics , communication , biology
The management of multiple sclerosis during pregnancy has changed in recent years; it is no longer viewed as hindering the evolution of the disease. Lower relapse rates are expected during gestation, while the early puerperium may be more critical. Case report We present two cases of active relapse‐remitting multiple sclerosis in pregnant women with different clinical courses, mirroring the disease heterogeneity and unpredictability. The first one, despite the ongoing activity, had two uneventful pregnancies. The second woman, previously controlled, experienced an increase in the disease activity during pregnancy. Discussions The decision of maintaining disease‐modifying therapy throughout gestation could be a strategy to reduce postpartum relapses.