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Circulating exosomes cause loss of immunological balance in multiple sclerosis
Author(s) -
Kimura Kimitoshi,
Yamamura Takashi
Publication year - 2018
Publication title -
clinical and experimental neuroimmunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 15
ISSN - 1759-1961
DOI - 10.1111/cen3.12474
Subject(s) - microvesicles , multiple sclerosis , pathogenesis , immunology , balance (ability) , medicine , bystander effect , neuroscience , biology , microrna , genetics , gene
Circulating exosomes are involved in the pathogenesis of MS by suppressing the induction of Treg cells via let‐7i ‐ IGF1R / TGFBR1 pathway.