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Targeting human T‐lymphotropic virus type 1‐infected cells with an anti‐C‐C chemokine receptor 4 antibody in T‐lymphotropic virus type 1‐associated myelopathy
Author(s) -
Sato Tomoo,
Yamano Yoshihisa
Publication year - 2018
Publication title -
clinical and experimental neuroimmunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 15
ISSN - 1759-1961
DOI - 10.1111/cen3.12467
Subject(s) - virology , human t lymphotropic virus , cc chemokine receptors , antibody , myelopathy , ccr4 , virus , medicine , chemokine receptor ccr5 , chemokine receptor , chemokine , immunology , immune system , spinal cord , psychiatry
In this article, we introduce our findings from phase I/IIa trial of anti‐CCR4 antibody in patients with HAM/TSP. The study demonstrated the importance of targeting HTLV‐1‐infected cells for the treatment of HAM/TSP.
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