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Flotillin‐1/2 autoimmunity in a patient with marginal zone lymphoma
Author(s) -
Schuh Elisabeth,
Komorowski Lars,
Feuerecker Regina,
Forstpointner Roswitha,
Straube Andreas,
Kümpfel Tania
Publication year - 2018
Publication title -
clinical and experimental neuroimmunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 15
ISSN - 1759-1961
DOI - 10.1111/cen3.12464
Subject(s) - context (archaeology) , medicine , autoimmunity , splenic marginal zone lymphoma , antibody , immunology , biology , b cell , paleontology
The flotillin‐1/2 heterocomplex seems to be a potential autoantigen in a subset of about 1–2% multiple sclerosis (MS) patients. Rarely humoral central nervous system (CNS) autoimmunity against neural surface associated proteins has yet been linked to underlying latent hematologic malignancies. Herein, we demonstrate a case of inflammatory CNS disease with flotillin auto‐antibodies in the context of a marginal zone lymphoma.