Flotillin‐1/2 autoimmunity in a patient with marginal zone lymphoma | Zendy

Schuh Elisabeth | Zendy; Komorowski Lars | Zendy; Feuerecker Regina | Zendy; Forstpointner Roswitha | Zendy; Straube Andreas | Zendy; Kümpfel Tania | Zendy

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Flotillin‐1/2 autoimmunity in a patient with marginal zone lymphoma

Author(s) -

Schuh Elisabeth,

Komorowski Lars,

Feuerecker Regina,

Forstpointner Roswitha,

Straube Andreas,

Kümpfel Tania

Publication year - 2018

Publication title -

clinical and experimental neuroimmunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.297

H-Index - 15

ISSN - 1759-1961

DOI - 10.1111/cen3.12464

Subject(s) - context (archaeology) , medicine , autoimmunity , splenic marginal zone lymphoma , antibody , immunology , biology , b cell , paleontology

The flotillin‐1/2 heterocomplex seems to be a potential autoantigen in a subset of about 1–2% multiple sclerosis (MS) patients. Rarely humoral central nervous system (CNS) autoimmunity against neural surface associated proteins has yet been linked to underlying latent hematologic malignancies. Herein, we demonstrate a case of inflammatory CNS disease with flotillin auto‐antibodies in the context of a marginal zone lymphoma.

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