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Astroglial phagocytosis in central nervous system health and disease
Author(s) -
Yamasaki Ryo
Publication year - 2017
Publication title -
clinical and experimental neuroimmunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 15
ISSN - 1759-1961
DOI - 10.1111/cen3.12413
Subject(s) - phagocytosis , central nervous system , neuroscience , astrocyte , nervous system , biology , microglia , disease , immunology , medicine , pathology , inflammation
Phagocytosis by astrocytes is important in the developing brain and in central nervous system lesions. Astroglial phagocytosis usually contributes to the repair of damaged lesions, but, depending on the local milieu, astrocytes can become activated “A1” type astroglia, which release neurotoxic substances and accelerate regional damage.