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Genetic trade‐off: Resistance to malaria or susceptibility to multiple sclerosis
Author(s) -
Ochi Hirofumi
Publication year - 2017
Publication title -
clinical and experimental neuroimmunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 15
ISSN - 1759-1961
DOI - 10.1111/cen3.12412
Subject(s) - malaria , plasmodium falciparum , adaptation (eye) , biology , genetic predisposition , genetics , virology , evolutionary biology , immunology , gene , neuroscience
Many types of genetic variations have evolved in humans as a result of evolutionary adaptation to malaria. Steri et al. reported that a genetic variant that provided resistance to Plasmodium falciparum or Plasmodium vivax malaria might have increased the susceptibility to multiple sclerosis among Sardinians.