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Cerebrospinal fluid/serum immunoglobulin G quotient is predictive of unresponsiveness to intravenous methylprednisolone therapy for acute exacerbation of neuromyelitis optica spectrum disorder
Author(s) -
Okada Kazumasa
Publication year - 2016
Publication title -
clinical and experimental neuroimmunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 15
ISSN - 1759-1961
DOI - 10.1111/cen3.12327
Subject(s) - plasmapheresis , neuromyelitis optica , cerebrospinal fluid , medicine , methylprednisolone , intravenous immunoglobulin therapy , exacerbation , antibody , immunology , immunoglobulin g
Oji et al. have reported that a high quotient of cerebrospinal fluid/serum immunoglobulin G might predict unresponsiveness to intravenous methylprednisolone and indicate the need for early introduction of plasmapheresis. The usefulness and problems regarding the quotient of cerebrospinal fluid/serum immunoglobulin G in clinical practice is discussed.