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Synovitis, acne, pustulosis, hyperostosis and osteitis syndrome with trigeminal brainstem involvement
Author(s) -
Redondo Robles Laura,
Fernández Menéndez Santiago,
Galiana Ivars Alberto,
Vázquez Sánchez Fernando,
Tejada García Javier,
Guerra Laso Jose Manuel
Publication year - 2013
Publication title -
clinical and experimental neuroimmunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 15
ISSN - 1759-1961
DOI - 10.1111/cen3.12015
Subject(s) - pustulosis , sapho syndrome , medicine , hyperostosis , osteitis , dermatology , synovitis , acne , context (archaeology) , osteomyelitis , pathology , anatomy , arthritis , surgery , paleontology , biology
The synovitis, acne, pustulosis, hyperostosis and osteitis ( SAPHO ) syndrome is defined as the association of characteristic osteoarticular and dermatological manifestations. The diagnosis is based on clinical and radiological aspects, but in the recent years it has been described as an extension of other systems different from the skin and the bones. We report the first case of parenchymal brainstem trigeminal involvement in the context of clinically‐active SAPHO syndrome. We review the literature and discuss the underlying mechanism of this multi‐organ presentation.