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Phaeochromocytoma crisis
Author(s) -
Whitelaw B. C.,
Prague J. K.,
Mustafa O. G.,
Schulte K.M.,
Hopkins P. A.,
Gilbert J. A.,
McGregor A. M.,
Aylwin S. J. B.
Publication year - 2014
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/cen.12324
Subject(s) - medicine , blockade , endocrine system , hypertensive crisis , intensive care medicine , circulatory system , cardiology , blood pressure , receptor , hormone
Summary Phaeochromocytoma crisis is an endocrine emergency associated with significant mortality. There is little published guidance on the management of phaeochromocytoma crisis. This clinical practice update summarizes the relevant published literature, including a detailed review of cases published in the past 5 years, and a proposed classification system. We review the recommended management of phaeochromocytoma crisis including the use of alpha‐blockade, which is strongly associated with survival of a crisis. Mechanical circulatory supportive therapy (including intra‐aortic balloon pump or extra‐corporeal membrane oxygenation) is strongly recommended for patients with sustained hypotension. Surgical intervention should be deferred until medical stabilization is achieved.