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Metabolic syndrome is strictly associated with parental obesity beginning from childhood
Author(s) -
Monzani Alice,
Rapa Anna,
Fuiano Nicola,
Diddi Giuliana,
Prodam Flavia,
Bellone Simonetta,
Bona Gianni
Publication year - 2014
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/cen.12261
Subject(s) - metabolic syndrome , medicine , abdominal obesity , obesity , waist , insulin resistance , odds ratio , national cholesterol education program , population , childhood obesity , family history , endocrinology , pediatrics , overweight , environmental health
Summary Objective We aimed to identify potential correlates or risk factors for metabolic syndrome ( M et S ) in a cohort of schoolchildren. We quantified the prevalence of M et S , analysed the clustering of M et S components and described the distribution of metabolic parameters not included in M et S definition. Design Population‐based, cross‐sectional study. Patients and measurements A total of 489 children (6·7–13 years) representing the 92·6% of the whole school population between the 1st year of primary school and the 2nd year of junior high school living in a centre of southern Italy. Weight, height, waist circumference, blood pressure ( BP ), laboratory parameters (indexes of glucose metabolism, lipid profile and uric acid), anamnestic and parental information, lifestyle and dietary habits were collected. Dietary habits data were available only for 353 children. Results M et S prevalence was 9·8%. Of 48 children with M et S , 38 (79·2%) were simultaneously positive for abdominal obesity and elevated BP . In children with M et S , the prevalence of insulin resistance, high insulin, high non‐ HDL (high‐density lipoprotein) cholesterol and high uric acid was higher than in children without M et S . In 6·7–10‐year‐old children, only the presence of parental history of obesity [odds ratio ( OR ) = 4·3, 95% CI = 1·8–10·2] was higher in those with M et S than in those without. In 10·1–13‐year‐old children, the presence of parental history of obesity, the habits of no walking/cycling to school, long screen time and no breakfast consumption were higher in children with M et S than in those without, but only parental history of obesity (adjusted OR = 3·8, 95% CI = 1·7–8·4) remained significantly related to M et S in multivariate logistic regression. Conclusions Parental obesity was strictly associated with M et S in all children and should be considered in clinical practice. In older children, wrong lifestyle and dietary habits were related to parental obesity.