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Current level of glycaemic control and its associated factors in patients with type 2 diabetes across Europe: data from the PANORAMA study
Author(s) -
de PablosVelasco Pedro,
Parhofer Klaus G,
Bradley Clare,
Eschwège Eveline,
Gönder-Frederick Linda,
Maheux Pierre,
Wood Ian,
Simon Dominique
Publication year - 2014
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/cen.12119
Subject(s) - medicine , type 2 diabetes , multivariate analysis , body mass index , diabetes mellitus , cross sectional study , regimen , panorama , medical record , bivariate analysis , endocrinology , statistics , mathematics , pathology , computer science , computer vision
Objective To provide an update on glycaemic control in European patients with type 2 diabetes based on data from the nine‐country, cross‐sectional PANORAMA study ( NCT 00916513). Design Post‐hoc analysis to report the number of patients achieving/not achieving glycaemic goal (HbA 1c <7%). Patients Patients were randomly or consecutively selected from physician practices in nine countries. Eligible patients were aged ≥40 years, diagnosed with type 2 diabetes >1 year prior to study entry, and had an available medical record of >1 year. Measurements All data were collected at a single visit, including HbA 1c measurement using a common device (A1 CN ow ® ). Bivariate and multivariate analyses were used to investigate factors associated with not reaching glycaemic goal. Results Of 5817 patients enrolled (aged 65·9 ± 10·4 years, 53·7% male), 37·4% had an HbA 1c ≥7%; (range 25·9% in The Netherlands to 52·0% in Turkey). In adjusted multivariate analyses, higher individual glycaemic target, younger age, poor physician‐reported patient adherence to lifestyle/medication, longer diabetes duration, increasing treatment regimen complexity and physician‐reported patient's unwillingness to intensify treatment were associated with not achieving goal. However, bivariate analyses also found gender, socioeconomic factors, body mass index, rate of complications and hypoglycaemia to be associated with not achieving goal. Conclusions In PANORAMA, 37·4% of patients enrolled were not at glycaemic goal. Factors relating to patient characteristics, physician selection of individualized HbA 1c target and diabetes itself (longer duration, more complex treatment) were strongly associated with not achieving goal. Further studies are warranted to explore these associations and evaluate strategies for improving glycaemic control.