Cervical cytomegalovirus reactivation, cytokines and spontaneous preterm birth in Kenyan women | Zendy

Begnel E. R. | Zendy; Drake A. L. | Zendy; Kinuthia J. | Zendy; Matemo D. | Zendy; Huang M.L. | Zendy; Ásbjörnsdóttir K. H. | Zendy; Chohan V. | Zendy; BeimaSofie K. | Zendy; JohnStewart G. | Zendy; Lehman D. | Zendy; Slyker J. | Zendy

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Cervical cytomegalovirus reactivation, cytokines and spontaneous preterm birth in Kenyan women

Author(s) -

Begnel E. R.,

Drake A. L.,

Kinuthia J.,

Matemo D.,

Huang M.L.,

Ásbjörnsdóttir K. H.,

Chohan V.,

BeimaSofie K.,

JohnStewart G.,

Lehman D.,

Slyker J.

Publication year - 2021

Publication title -

clinical & experimental immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.329

H-Index - 135

eISSN - 1365-2249

pISSN - 0009-9104

DOI - 10.1111/cei.13558

Subject(s) - medicine , odds ratio , obstetrics , pregnancy , cytomegalovirus , prospective cohort study , gestation , cervix , gestational age , premature birth , human cytomegalovirus , confidence interval , case control study , immunology , herpesviridae , viral disease , virus , biology , genetics , cancer

Cervical CMV shedding may increase risk of spontaneous preterm birth (sPTB) through the release of inflammatory cytokines in the cervix. Among 86 women who had a sPTB and 86 matched controls from western Kenya, cervical CMV levels were not significantly associated with sPTB but were significantly associated with higher levels of cervical levels of inflammatory cytokine interleukin‐6.

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