The role of interleukin‐18 in the diagnosis and monitoring of hemophagocytic lymphohistiocytosis/macrophage activation syndrome – a systematic review
Author(s) -
Krei J. M.,
Møller H. J.,
Larsen J. B.
Publication year - 2021
Publication title -
clinical & experimental immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 135
eISSN - 1365-2249
pISSN - 0009-9104
DOI - 10.1111/cei.13543
Subject(s) - macrophage activation syndrome , hemophagocytic lymphohistiocytosis , medicine , immunology , biomarker , interleukin 18 , arthritis , cytokine , disease , biology , biochemistry
Systematic review of studies investigating interleukin‐18 (IL‐18) in hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS).Serum IL‐18 appears to discriminate well between HLH/MAS and other inflammatory conditions.
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