Lipid antigens in bile from patients with chronic liver diseases activate natural killer T cells
Author(s) -
Valestrand L.,
Berntsen N. L.,
Zheng F.,
Schrumpf E.,
Hansen S. H.,
Karlsen T. H.,
Blumberg R. S.,
Hov J. R.,
Jiang X.,
Melum E.
Publication year - 2021
Publication title -
clinical & experimental immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 135
eISSN - 1365-2249
pISSN - 0009-9104
DOI - 10.1111/cei.13541
Subject(s) - natural killer t cell , antigen , biology , cd1d , immunology , microbiology and biotechnology , cd8
Bile from patients with chronic liver diseases contains antigens that activate natural killer T cells, an important subgroup of liver lymphocytes . Activation of this immunological pathway suggests that bile antigens may be important in inflammatory bile duct diseases.
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