Open AccessInterleukin‐35 has a tumor‐promoting role in hepatocellular carcinoma
Author(s) -
Liu X.,
Ren H.,
Guo H.,
Wang W.,
Zhao N.
Publication year - 2021
Publication title -
clinical & experimental immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 135
eISSN - 1365-2249
pISSN - 0009-9104
DOI - 10.1111/cei.13535
Subject(s) - biology , cd8 , tumor microenvironment , immune system , cytokine , cancer research , t cell , immunology , flow cytometry , tumor infiltrating lymphocytes , interleukin , microbiology and biotechnology
IL‐35 highly expressed in HCC tumor tissues which exerted an immune suppressive role in HCC tumor microenvironments through affecting inhibitor receptor expression and cytokine secretion of CD4 + and CD8 + T cells.
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