Open AccessSimultaneous testing of immunological sensitization to multiple antigens in sarcoidosis reveals an association with inorganic antigens specifically related to a fibrotic phenotype
Author(s) -
Beijer E.,
Kraaijvanger R.,
Roodenburg C.,
Grutters J. C.,
Meek B.,
Veltkamp M.
Publication year - 2021
Publication title -
clinical & experimental immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 135
eISSN - 1365-2249
pISSN - 0009-9104
DOI - 10.1111/cei.13519
Subject(s) - sarcoidosis , immunology , antigen , medicine , elispot , sensitization , pathogenesis , pathology , cd8
Sensitization to inorganic but not to organic antigens, was associated with sarcoidosis in a cohort of over 100 Dutch patients. Metal and silica sensitized patients were at greater risk of developing fibrosis 5 years after diagnosis.
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