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Kawasaki disease for the paediatric dermatologist: skin manifestations and new insights into the pathophysiology
Author(s) -
Piram M.,
Burns J. C.
Publication year - 2021
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.14558
Subject(s) - medicine , mucocutaneous zone , kawasaki disease , dermatology , pathophysiology , disease , mucocutaneous lymph node syndrome , skin lesion , multisystem disease , intensive care medicine , pediatrics , pathology , surgery , artery
Summary Early diagnosis of Kawasaki disease (KD) is critical to allow prompt initiation of treatment and avoid cardiac complications. All children with KD have fever accompanied by clinical signs, with four of the five classic criteria for complete KD being mucocutaneous, thus creating an important role for dermatologists. Moreover, dermatologists must be familiar with other dermatological findings that are not included in the American Heart Association classification criteria but can support the diagnosis, particularly in incomplete forms of the disease. We review the skin manifestations described for KD and perform an overview of pathophysiological advances and new treatments.