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Lactate dehydrogenase in dermatology practice
Author(s) -
Livesey A.,
Garty F.,
Shipman A. R.,
Shipman K. E.
Publication year - 2020
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.14134
Subject(s) - lactate dehydrogenase , medicine , lymphoma , dermatology , anaerobic exercise , l lactate dehydrogenase , pathology , enzyme , chemistry , biochemistry , physiology
Summary Lactate dehydrogenase (LDH) is used in dermatology practice, particularly as a prognostic marker for cutaneous lymphoma. LDH is an intracellular enzyme involved in anaerobic glycolysis, and is found at low concentrations in the blood. LDH is produced in every tissue, thus cell damage releases LDH into the circulation, so the causes of elevated LDH levels are multiple. The utility of LDH in dermatology practice is reviewed, alongside current diagnostic and staging guidelines.