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What's new in atopic eczema? An analysis of systematic reviews published in 2015. Part 2: prevention and treatment
Author(s) -
LloydLavery A.,
Rogers N. K.,
Davies E.,
Grindlay D. J. C.,
Thomas K. S.
Publication year - 2018
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.13554
Subject(s) - medicine , systematic review , atopic dermatitis , cochrane library , adverse effect , medline , quality of evidence , pediatrics , pregnancy , intensive care medicine , meta analysis , dermatology , political science , law , genetics , biology
Summary This review forms part of a series of annual updates that summarize the evidence base for atopic eczema ( AE ), providing a succinct guide for clinicians and patients. It provides a summary of key findings from 26 systematic reviews that were published during 2015, and focuses on the treatment and prevention of AE . For systematic reviews on the epidemiology and methodological issues, see Part 1 of this update. Topical corticosteroid withdrawal syndrome, ‘steroid addiction’, has been evaluated in a high‐quality systematic review, which helps better define this entity and the risk factors for it. A Cochrane Review has not demonstrated any association between topical corticosteroid use in pregnancy and adverse outcomes, although very large quantities of potent/very potent topical corticosteroids may be associated with reduced birth weight. House dust mite avoidance strategies do not appear to prevent AE . Exposure to probiotics prenatally and in early infancy may help prevent AE , but there is no evidence that maternal diet or supplementation has a preventative effect.