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Intravenous immunoglobulins in dermatology. Part 1: biological mechanisms and methods of administration
Author(s) -
Forbat E.,
Ali F. R.,
AlNiaimi F.
Publication year - 2018
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.13553
Subject(s) - medicine , adverse effect , dosing , intravenous immunoglobulins , antibody , intensive care medicine , dermatology , clinical trial , randomized controlled trial , mechanism (biology) , immunology , pharmacology , pathology , philosophy , epistemology
Summary Intravenous immunoglobulin ( IVI g) is a solution of human IgG, salt, sugars and solvents, which is used to treat a multitude of diseases. Although IVI g has been known to treat many diseases safely and successfully, there are relatively few supporting randomized controlled trials. In this article, we review the biological mechanisms of IVI g in dermatological disorders and the practicalities of its use, including its mechanism of action, dosing, availability, costs and adverse effects.