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Palmar fasciitis and polyarthritis, a rare paraneoplastic syndrome related to ovarian cancer
Author(s) -
Marcke C.,
Seront E.,
Docquier C.,
Filleul B.
Publication year - 2017
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.13071
Subject(s) - medicine , polyarthritis , fasciitis , malignancy , dermatology , fascia , ovarian cancer , contracture , cancer , arthritis , pathology , surgery
Summary Palmar fasciitis and polyarthritis syndrome ( PFPAS ) is an uncommon disorder characterized by diffuse inflammation of the palmar fascia, tendon sheaths, and joints of the fingers and wrists, which rapidly progresses to flexion contracture of the hands. This paraneoplastic syndrome, originally linked to ovarian carcinoma, has also been associated with multiple different malignancies. As PFPAS usually precedes the detection of cancer, its symptoms should raise the suspicion of an underlying malignancy and should be thoroughly investigated.