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Paraneoplastic pityriasis rubra pilaris: case report and literature review
Author(s) -
BarIlan E.,
Gat A.,
Sprecher E.,
Zeeli T.
Publication year - 2017
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.13009
Subject(s) - pityriasis rubra pilaris , medicine , dermatology , malignancy , fulminant , disease , medline , pathology , surgery , psoriasis , political science , law
Summary Pityriasis rubra pilaris ( PRP ; MIM 173200) is an uncommon papulosquamous inflammatory dermatosis. Only a few cases of PRP associated with an underlying malignancy have been documented. We investigated a 59‐year‐old patient presenting with a fulminant form of PRP recalcitrant to systemic retinoid therapy, in whom the skin disease heralded a diagnosis of cholangiocarcinoma. We searched the MEDLINE database to find articles reporting on similar associations of PRP with malignancies. We identified 10 studies linking PRP and malignancies, but an association between PRP and cholangiocarcinoma has not yet been reported.