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Novel application of high‐dose rate brachytherapy for severe, recalcitrant palmoplantar pustulosis
Author(s) -
Timerman D.,
Devlin P. M.,
Nambudiri V. E.,
Wright N. A.,
Vleugels R. A.,
Clark R. A.,
Kupper T. S.,
Merola J. F.,
Patel M.
Publication year - 2016
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.12803
Subject(s) - palmoplantar pustulosis , medicine , brachytherapy , ankle , dermatology , refractory (planetary science) , pustulosis , limiting , psoriasis , radiology , surgery , radiation therapy , osteomyelitis , physics , osteitis , astrobiology , mechanical engineering , engineering
Summary Palmoplantar pustulosis ( PPP ) is a chronic pustular dermatitis of the palms and soles, which is frequently associated with significant pruritus and pain, often limiting daily activities. We present the case of a 36‐year‐old man with severe PPP who had treatment failure with multiple medical therapies but showed marked improvement with high‐dose rate brachytherapy. Brachytherapy has the advantage of providing a conformal dose distribution over complex curved surfaces, such as the foot and ankle. Our observations suggest that brachytherapy may be a well‐tolerated treatment option for patients with severe, refractory PPP .