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Saggy skin as a presenting sign of angioimmunoblastic T‐cell lymphoma
Author(s) -
Maher N. G.,
Chiang Y. Z.,
Badoux X.,
Vonthethoff L. W.,
Murrell D. F.
Publication year - 2016
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.12773
Subject(s) - angioimmunoblastic t cell lymphoma , erythroderma , medicine , lymphoma , dermatology , pathology , chemotherapy , t cell , immunology , immune system
Summary Angioimmunoblastic T‐cell lymphoma ( AITL ) is a rare, aggressive form of peripheral T‐cell lymphoma that has a variety of cutaneous manifestations. To our knowledge, saggy skin has not been documented as one of these manifestations. We report a case of a patient with angioimmunoblastic T‐cell lymphoma presenting initially with pruritus and saggy skin, which later progressed into erythroderma despite chemotherapy; the disease eventually resolved with autologous stem cell transplant. Appreciating the cutaneous manifestations of AITL may allow for earlier diagnosis and treatment.