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Successful treatment of generalized granuloma annulare with adalimumab
Author(s) -
Mahmood T.,
Mansouri B.,
Menter A.
Publication year - 2015
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.12598
Subject(s) - adalimumab , medicine , granuloma annulare , regimen , dermatology , lesion , surgery , tumor necrosis factor alpha
Summary We report the case of a 64 year‐old woman who demonstrated resolution of recalcitrant, generalized granuloma annulare ( GA ) following treatment with adalimumab. After showing little response to other treatment techniques, such as steroids and a triple antibiotic regimen, the patient was started on adalimumab. Within 3 months, she showed almost complete resolution of lesions. Within 6 months, she was completely lesion‐free, and remained clear following 12 months of adalimumab therapy. This case provides further evidence that tumour necrosis factor‐α inhibitors may be a treatment option for patients with recalcitrant, generalized GA .

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