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Clinicopathological features and expression of four keratins ( K 10, K 14, K 17 and K 19) in six cases of eruptive vellus hair cysts
Author(s) -
Shi G.,
Zhou Y.,
Cai Y.X.,
Li S.J.,
Fan Y.M.
Publication year - 2014
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.12337
Subject(s) - vellus hair , pathological , keratin , pathology , histopathology , biology , immunohistochemistry , medicine , anatomy , scalp
Summary Six cases of eruptive vellus hair cysts ( EVHC ) were evaluated for histopathology and the immunohistochemical profile of K i‐67 and four keratins ( K 10, K 14, K 17 and K 19). The pathological hallmark of EVHC was the existence of vellus hair shafts within the cystic cavity, but atypical pathological changes included two or three cysts and a foreign‐body granuloma in three cases. Our results demonstrate that atypical pathological changes are not uncommon in EVHC , and indicate that based on keratin expression, it is likely that EVHC is derived from the infrainfundibulum and sebaceous duct.