Clinicopathological features and expression of four keratins ( K 10,  K 14,  K 17 and  K 19) in six cases of eruptive vellus hair cysts | Zendy

Shi G. | Zendy; Zhou Y. | Zendy; Cai Y.X. | Zendy; Li S.J. | Zendy; Fan Y.M. | Zendy

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Clinicopathological features and expression of four keratins ( K 10, K 14, K 17 and K 19) in six cases of eruptive vellus hair cysts

Author(s) -

Shi G.,

Zhou Y.,

Cai Y.X.,

Li S.J.,

Fan Y.M.

Publication year - 2014

Publication title -

clinical and experimental dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.587

H-Index - 78

eISSN - 1365-2230

pISSN - 0307-6938

DOI - 10.1111/ced.12337

Subject(s) - vellus hair , pathological , keratin , pathology , histopathology , biology , immunohistochemistry , medicine , anatomy , scalp

Summary Six cases of eruptive vellus hair cysts ( EVHC ) were evaluated for histopathology and the immunohistochemical profile of K i‐67 and four keratins ( K 10, K 14, K 17 and K 19). The pathological hallmark of EVHC was the existence of vellus hair shafts within the cystic cavity, but atypical pathological changes included two or three cysts and a foreign‐body granuloma in three cases. Our results demonstrate that atypical pathological changes are not uncommon in EVHC , and indicate that based on keratin expression, it is likely that EVHC is derived from the infrainfundibulum and sebaceous duct.

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