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Diclofenac‐induced pseudoporphyria; an under‐recognized condition?
Author(s) -
Turnbull N.,
Callan M.,
Staughton R. C. D.
Publication year - 2014
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.12313
Subject(s) - diclofenac , porphyria cutanea tarda , medicine , dermatology , nonsteroidal , porphyria , naproxen , psoriasis , pathology , pharmacology , alternative medicine
Summary Pseudoporphyria is a photodistributed bullous disorder that is clinically and histologically similar to porphyria cutanea tarda ( PCT ), but without abnormal porphyrin biochemistry. Renal failure, dialysis, excessive ultraviolet A and medications, particularly nonsteroidal anti‐inflammatory drugs ( NSAID s), have been associated with pseudoporphyria. We report a case of diclofenac‐induced pseudoporphyria in a man with psoriatic arthritis. To our knowledge, this is only the second reported case of pseudoporphyria associated with diclofenac. Diclofenac has hitherto been considered by many dermatologists as a safe alternative in NSAID ‐induced pseudoporphyria.