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Successful renal transplant in a patient with non‐ H erlitz junctional epidermolysis bullosa
Author(s) -
Ungureanu S.,
Adni T.,
Brown T.,
Inston N.,
Heagerty A.
Publication year - 2014
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/ced.12300
Subject(s) - junctional epidermolysis bullosa (veterinary medicine) , medicine , epidermolysis bullosa , nephropathy , transplantation , dermatology , kidney transplantation , surgery , laminin , endocrinology , genetics , cell , biology , diabetes mellitus
Summary Non‐ H erlitz junctional epidermolysis bullosa ( NH ‐ JEB ) is a very rare inherited disorder, with an array of complications. We present the case of a 33‐year‐old patient of C hinese origin, diagnosed with NH ‐ JEB in childhood, who developed severe I g A nephropathy. His renal impairment was initially treated by haemodialysis. He underwent successful renal transplantation, resulting in normalization of his renal function. To our knowledge, this is the first report of renal transplantation in a patient with epidermolysis bullosa, which should support use of this intervention in other similar cases.