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Atopy in people aged 40 years and over: Relation to airflow limitation
Author(s) -
GuevaraRattray E. M.,
Garden F. L.,
James A. L.,
WoodBaker R.,
Abramson M. J.,
Johns D. P.,
Sonia Buist A.,
Burney P. G. J.,
Haydn Walters E.,
Toelle B. G.,
Marks G. B.
Publication year - 2017
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/cea.13038
Subject(s) - atopy , airflow , relation (database) , medicine , gerontology , asthma , immunology , computer science , engineering , mechanical engineering , database
Summary Background Previous studies have reached conflicting conclusions about the role of atopy as a risk factor for COPD. In part, this is attributable to variation in the definitions of airflow limitation and the treatment of people with asthma. Objective To establish whether there is any independent association between atopy and post‐bronchodilator airflow limitation in the general population aged 40 years and over. Methods A cross‐sectional survey was conducted in a general population sample of 2415 people aged 40 years and over in Australia. A history of ever being diagnosed with asthma was elicited by questionnaire. Atopy was defined as any skin prick test weal to common aeroallergens ≥4 mm. Airflow limitation was defined as post‐bronchodilator spirometric (FEV 1 /FVC) ratio