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Synthesis and anti‐inflammatory activity of diversified heterocyclic systems
Author(s) -
Bari Ahmed,
Grenier Daniel,
Azelmat Jabrane,
Syed Saeed Ali,
AlObaid Abdulrahman M.,
Hosten Eric C.
Publication year - 2019
Publication title -
chemical biology and drug design
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 77
eISSN - 1747-0285
pISSN - 1747-0277
DOI - 10.1111/cbdd.13576
Subject(s) - anti inflammatory , combinatorial chemistry , chemistry , molecule , microanalysis , stereochemistry , organic chemistry , pharmacology , biology
In continuation with our research program on the development of novel bioactive molecules, we report herein the design and synthesis of a series of diversified heterocycles ( 4 – 22 ). The synthesized compounds were evaluated for their anti‐inflammatory activity. The chemical structures of the newly synthesized compounds have been confirmed by NMR, FTIR, and microanalysis.