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Recent drug therapies for corneal neovascularization
Author(s) -
Liu Xinyao,
Wang Shurong,
Wang Xuanzhong,
Liang Jiaming,
Zhang Yan
Publication year - 2017
Publication title -
chemical biology and drug design
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 77
eISSN - 1747-0285
pISSN - 1747-0277
DOI - 10.1111/cbdd.13018
Subject(s) - corneal neovascularization , drug , medicine , pharmacology , neovascularization , ophthalmology , angiogenesis , cancer research
Corneal neovascularization ( CNV ) is a common pathological change in ocular surface diseases. It is not only the factor that affects vision but also the main cause for corneal graft failure. Based on the mechanism of CNV , many achievements have been developed to suppress the formation of CNV . There are certain novel drugs such as aflibercept, gold nanoparticles, and netrins which provide us with new clues to treat CNV . However, we still need to develop more effective therapeutic drugs. It is of great significance to develop new effective drugs to suppress the occurrence of CNV . In this paper, recent drug therapies for CNV are reviewed. The electronic database (PubMed) is searched for relative basic research and randomized clinical trials that are published recently.