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Beyond the Hundred Dollar Genome – Drug Discovery Futures
Author(s) -
Selwood David L.
Publication year - 2013
Publication title -
chemical biology and drug design
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 77
eISSN - 1747-0285
pISSN - 1747-0277
DOI - 10.1111/cbdd.12088
Subject(s) - computational biology , drug discovery , in silico , genome , human genome , computer science , cheminformatics , whole genome sequencing , bioinformatics , biology , genetics , gene
The advent of silicon chip based technologies for genome sequencing promises continuing exponential falls in the reagent costs of sequencing. When every patient has a full genome sequence as part of their medical records the science of drug discovery and drug design must adapt and improve to meet this challenge. This series covers computational, and experimental approaches for small molecules and biologics. From the virtual patient – a computational model of a complete human being, through in silico screening to RNA editing and antibody directed therapies.

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