Open AccessRomidepsin (FK228) and its analogs directly inhibit PI3 kinase activity and induce apoptosis. An enlarged picture around the ligand is shown. A ball and stick model shows the reduced Romidepsin in the PI3 kinase ribbon and line drawing. See also Saijo, K., et al.
Author(s) -
Saijo Ken,
Katoh Tadashi,
Shimodaira Hideki,
Oda Akifumi,
Takahashi Ohgi,
Ishioka Chikashi
Publication year - 2012
Publication title -
cancer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 141
eISSN - 1349-7006
pISSN - 1347-9032
DOI - 10.1111/cas.12016
Subject(s) - romidepsin , ligand (biochemistry) , chemistry , computer science , biochemistry , receptor , gene , histone deacetylase , histone